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Yes. TAP Air Portugal flies nonstop from São Paulo (GRU) to Porto (OPO), 3–4 times a week. The flight takes about 10h 59m and covers 5,083 miles (8,180 km).
TAP Air Portugal operates nonstop flights from São Paulo to Porto.
The nonstop flight from São Paulo to Porto takes ~10h 59m (approximately 8180 km).
Nonstop flights from São Paulo to Porto operate 3–4 times a week.