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Yes. Azul, Gol, LATAM and LATAM Brasil fly nonstop from São Paulo (GRU) to Cuiabá (CGB), several times daily. The flight takes about 2h 12m and covers 826 miles (1,329 km).
Azul, Gol, LATAM, LATAM Brasil operate nonstop flights from São Paulo to Cuiabá.
The nonstop flight from São Paulo to Cuiabá takes ~2h 12m (approximately 1329 km).
Nonstop flights from São Paulo to Cuiabá operate several times daily.