Direct flights from St Louis to Chicago STL → MDW

Southwest Airlines operates nonstop flights from St Louis (STL) to Chicago (MDW). The nonstop flight takes around ~0h 30m, covering 251 miles (404 km). Updated 11 June 2026.

Southwest Airlines WN

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More nonstops from St Louis

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Frequently asked questions

Is there a direct flight from St Louis to Chicago?

Yes, Southwest Airlines operates nonstop flights from St Louis (STL) to Chicago (MDW).

Which airlines fly direct from St Louis to Chicago?

Southwest Airlines operates nonstop flights from St Louis to Chicago.

How long is the flight from St Louis to Chicago?

The nonstop flight from St Louis to Chicago takes ~0h 30m (approximately 404 km).

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