Direct flights from St Louis to Chicago STL → MDW
Southwest Airlines flies nonstop from St Louis (STL) to Chicago (MDW), several times daily. The flight takes about 1h 1m and covers 251 miles (404 km). Arrivals run on time 76.7% at STL and 72.8% at MDW — BTS data for the last three months, counting arrivals within 15 minutes of schedule. Schedule data from 27 July 2026.
🔔 Watch STL → MDW
We'll run this search daily and email you the cheapest direct fares we find.
Free · checked daily · one-click unsubscribe
Southwest Airlines
WN
Departure Schedule typical week
Typical weekly schedule · 36 flights per week (~5 per day) · Updated 34d ago
Southwest Airlines
Frequently asked questions
Is there a direct flight from St Louis to Chicago?
Yes, Southwest Airlines operates nonstop flights from St Louis (STL) to Chicago (MDW).
Which airlines fly direct from St Louis to Chicago?
Southwest Airlines operates nonstop flights from St Louis to Chicago.
How long is the flight from St Louis to Chicago?
The nonstop flight from St Louis to Chicago takes ~1h 1m (approximately 404 km).
How often do direct flights operate from St Louis to Chicago?
Nonstop flights from St Louis to Chicago operate multiple daily — 36 flights per week (~5 per day).
What is the on-time performance for flights from St Louis to Chicago?
Arrivals run on time 76.7% at STL and 72.8% at MDW — BTS data for the last three months, counting arrivals within 15 minutes of schedule.
What days of the week are there direct flights from St Louis to Chicago?
Direct flights from St Louis to Chicago operate every day of the week.
Explore More
Scout — our search agent — hunts nonstop fares from St Louis every night and pings you when one's worth booking.
Watch it work →