Direct flights from Chicago to St Louis MDW → STL
Southwest Airlines operates nonstop flights from Chicago (MDW) to St Louis (STL). The nonstop flight takes around ~0h 30m, covering 251 miles (404 km). Updated 11 June 2026.
MDW
→
STL
Round trip
1 adult
Economy
Pick dates
Southwest Airlines
WN
Departure Schedule next 7 days
Sign up to see St Louis schedule from MDW
Already have an account? Sign in
Frequently asked questions
Is there a direct flight from Chicago to St Louis?
Yes, Southwest Airlines operates nonstop flights from Chicago (MDW) to St Louis (STL).
Which airlines fly direct from Chicago to St Louis?
Southwest Airlines operates nonstop flights from Chicago to St Louis.
How long is the flight from Chicago to St Louis?
The nonstop flight from Chicago to St Louis takes ~0h 30m (approximately 404 km).