Direct flights from St Louis to Columbus

  • ~3 flights a day
  • Southwest Airlines

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When the nonstops leave

Typical weekly schedule · 20 flights per week (~3 per day) · Updated 81d ago

Most leave in the morning.

Morning before noon 15 a week

Arrive the same day

5:05 AM 7:40 AMTue, Wed 7:55 AMThu, Fri 8:10 AM4 days a week
Afternoon noon – 6 PM 4 a week

Arrive the same day

4:20 PMSat 4:30 PMMon, Thu, Fri
Evening after 6 PM 1 a week

Arrive the next morning

8:55 PMSun
Southwest Airlines Departs Terminal 2 Arrives Terminal A

More nonstops from St Louis

STL → MCO Orlando 2 airlines STL → SLC Salt Lake City 2 airlines STL → BNA Nashville STL → BWI Baltimore STL → DAL Dallas STL → MCI Kansas City STL → MDW Chicago STL → PIT Pittsburgh CMH → STL The return trip STL All nonstops from St Louis CMH All nonstops from Columbus

Frequently asked questions

Is there a direct flight from St Louis to Columbus?

Yes. Southwest Airlines flies nonstop from St Louis (STL) to Columbus (CMH), daily. The flight takes about 1h 21m and covers 408 miles (657 km). Schedule data from 30 July 2026.

Which airlines fly direct from St Louis to Columbus?

Southwest Airlines operates nonstop flights from St Louis to Columbus.

How long is the flight from St Louis to Columbus?

The nonstop flight from St Louis to Columbus takes ~1h 21m (approximately 657 km).

How often do direct flights operate from St Louis to Columbus?

Nonstop flights from St Louis to Columbus operate daily — 20 flights per week (~3 per day).

What days of the week are there direct flights from St Louis to Columbus?

Direct flights from St Louis to Columbus operate every day of the week.