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Yes. Avianca, Vuela El Salvador and TAGAirlines fly nonstop from San Salvador (SAL) to Guatemala City (GUA), several times daily. The flight takes about 46m and covers 126 miles (203 km).
Avianca, Vuela El Salvador, TAGAirlines operate nonstop flights from San Salvador to Guatemala City.
The nonstop flight from San Salvador to Guatemala City takes ~46m (approximately 203 km).
Nonstop flights from San Salvador to Guatemala City operate several times daily.