Direct flights from Chicago to Des Moines ORD → DSM
American Airlines and United Airlines operate nonstop flights from Chicago (ORD) to Des Moines (DSM). The nonstop flight takes around ~0h 36m, covering 298 miles (480 km) and operates multiple daily. Updated 28 June 2026.
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American Airlines
AA
United Airlines
UA
Departure Schedule next 7 days
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Frequently asked questions
Is there a direct flight from Chicago to Des Moines?
Yes, American Airlines and United Airlines operate nonstop flights from Chicago (ORD) to Des Moines (DSM).
Which airlines fly direct from Chicago to Des Moines?
American Airlines, United Airlines operate nonstop flights from Chicago to Des Moines.
How long is the flight from Chicago to Des Moines?
The nonstop flight from Chicago to Des Moines takes ~0h 36m (approximately 480 km).
How often do direct flights operate from Chicago to Des Moines?
Nonstop flights from Chicago to Des Moines operate multiple daily.