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Yes. Avianca and LATAM fly nonstop from Manta (MEC) to Quito (UIO), several times daily. The flight takes about 51m and covers 170 miles (274 km).
Avianca, LATAM operate nonstop flights from Manta to Quito.
The nonstop flight from Manta to Quito takes ~51m (approximately 274 km).
Nonstop flights from Manta to Quito operate several times daily.