Direct flights from Guayaquil to Medellín GYE → MDE
Avianca operates nonstop flights from Guayaquil (GYE) to Medellín (MDE). The nonstop flight takes around ~1h 19m, covering 652 miles (1,050 km) and operates 3–4×/week. Updated 28 June 2026.
GYE
→
MDE
Round trip
1 adult
Economy
Pick dates
📬 Cheap nonstop deals from Guayaquil
We'll email you when a fare from GYE drops well below normal. Free, weekly, no password needed.
Free · weekly digest · no password needed
Avianca
AV
Departure Schedule next 7 days
Sign up to see Medellín schedule from GYE
Already have an account? Sign in
Frequently asked questions
Is there a direct flight from Guayaquil to Medellín?
Yes, Avianca operates nonstop flights from Guayaquil (GYE) to Medellín (MDE).
Which airlines fly direct from Guayaquil to Medellín?
Avianca operates nonstop flights from Guayaquil to Medellín.
How long is the flight from Guayaquil to Medellín?
The nonstop flight from Guayaquil to Medellín takes ~1h 19m (approximately 1050 km).
How often do direct flights operate from Guayaquil to Medellín?
Nonstop flights from Guayaquil to Medellín operate 3–4×/week.