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Yes. Avianca and LATAM fly nonstop from Guayaquil (GYE) to Isla Baltra (GPS), several times daily. The flight takes about 2h and covers 727 miles (1,170 km).
Avianca, LATAM operate nonstop flights from Guayaquil to Isla Baltra.
The nonstop flight from Guayaquil to Isla Baltra takes ~2h (approximately 1170 km).
Nonstop flights from Guayaquil to Isla Baltra operate several times daily.