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Yes. Ryanair flies nonstop from Perugia (PEG) to Brindisi (BDS). The flight takes about 1h 10m and covers 326 miles (525 km).
Ryanair operates nonstop flights from Perugia to Brindisi.
The nonstop flight from Perugia to Brindisi takes ~1h 10m (approximately 525 km).