Direct flights from Mexico City to Medellín MEX → MDE

Aeromexico and Avianca fly nonstop from Mexico City (MEX) to Medellín (MDE), daily. The flight takes about 4h 17m and covers 1,834 miles (2,952 km). Round-trip fares typically run around $622, with recent bookable fares from $436. Fares last checked 30 August 2026.

60-day flexibility overview based on 8 recent fares across the next 60 days

Cheapest
$436
Typical
$622
Most expensive
$744

Cheapest combos

Aeromexico Best
Fri Oct 16 17:55 → 23:30
Fri Oct 23 01:00 → 04:25 7 nights
$436 Book →
Aeromexico
Sun Sep 13 17:55 → 23:30
Sat Sep 19 23:50 → 03:20 6 nights
$604 Book →
Avianca
Fri Oct 16 05:00 → 10:20
Fri Oct 23 22:35 → 02:00 7 nights
$661 Book →

Prices last updated about 2 hours ago. Fares change frequently — check the airline for current pricing.

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Aeromexico AM Avianca AV

Nonstop departures observed in recent fares

Across 4 recent dates we priced, Mexico City (MEX) to Medellín (MDE) showed up to 2 nonstop departures a day, with the earliest around 05:00 and the latest around 17:55, operated by Aeromexico and Avianca.

05:00 17:35 17:55

Departure times seen while pricing this route over the last few weeks — a sample, not the full timetable. Airlines adjust schedules seasonally.

More nonstops from Mexico City

MEX → LAX Los Angeles 5 airlines MEX → ORD Chicago 5 airlines MEX → TIJ Tijuana 5 airlines MEX → CUN Cancún 4 airlines MEX → IAH Houston 4 airlines MEX → JFK New York 4 airlines MEX → PVR Puerto Vallarta 4 airlines MEX → SJD San José del Cabo 4 airlines

Frequently asked questions

Is there a direct flight from Mexico City to Medellín?

Yes, Aeromexico and Avianca operate nonstop flights from Mexico City (MEX) to Medellín (MDE).

Which airlines fly direct from Mexico City to Medellín?

Aeromexico, Avianca operate nonstop flights from Mexico City to Medellín.

How long is the flight from Mexico City to Medellín?

The nonstop flight from Mexico City to Medellín takes ~4h 17m (approximately 2952 km).

How often do direct flights operate from Mexico City to Medellín?

Nonstop flights from Mexico City to Medellín operate daily.

How much is a round-trip flight from Mexico City to Medellín?

Round-trip flights from Mexico City (MEX) to Medellín (MDE) start at $436, with a typical fare around $622. Based on 8 recent fare combinations.

Explore More

MEX All direct flights from Mexico City MDE All direct flights from Medellín MDE → MEX Return: Medellín to Mexico City

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