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Yes. TransNusa and China Southern Airlines fly nonstop from Manado (MDC) to Guangzhou (CAN), daily. The flight takes about 4h and covers 1,698 miles (2,733 km).
TransNusa, China Southern Airlines operate nonstop flights from Manado to Guangzhou.
The nonstop flight from Manado to Guangzhou takes ~4h (approximately 2733 km).
Nonstop flights from Manado to Guangzhou operate daily.