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Yes. China Southern Airlines, Air Cambodia and Spring Airlines fly nonstop from Phnom Penh (KTI) to Guangzhou (CAN), several times daily. The flight takes about 2h 33m and covers 997 miles (1,605 km).
China Southern Airlines, Air Cambodia, Spring Airlines operate nonstop flights from Phnom Penh to Guangzhou.
The nonstop flight from Phnom Penh to Guangzhou takes ~2h 33m (approximately 1605 km).
Nonstop flights from Phnom Penh to Guangzhou operate several times daily.