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Yes. Lufthansa and Lufthansa City Airlines fly nonstop from Frankfurt (FRA) to Marseille (MRS), daily. The flight takes about 1h 30m and covers 482 miles (775 km).
Lufthansa, Lufthansa City Airlines operate nonstop flights from Frankfurt to Marseille.
The nonstop flight from Frankfurt to Marseille takes ~1h 30m (approximately 775 km).
Nonstop flights from Frankfurt to Marseille operate daily.