Direct flights from Detroit to St Louis DTW → STL
Delta Air Lines and Southwest Airlines operate nonstop flights from Detroit (DTW) to St Louis (STL). The nonstop flight takes around ~0h 53m, covering 439 miles (707 km) and operates multiple daily. Updated 29 June 2026.
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Delta Air Lines
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Southwest Airlines
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Departure Schedule next 7 days
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Frequently asked questions
Is there a direct flight from Detroit to St Louis?
Yes, Delta Air Lines and Southwest Airlines operate nonstop flights from Detroit (DTW) to St Louis (STL).
Which airlines fly direct from Detroit to St Louis?
Delta Air Lines, Southwest Airlines operate nonstop flights from Detroit to St Louis.
How long is the flight from Detroit to St Louis?
The nonstop flight from Detroit to St Louis takes ~0h 53m (approximately 707 km).
How often do direct flights operate from Detroit to St Louis?
Nonstop flights from Detroit to St Louis operate multiple daily.