Direct flights from Charleston to St Louis

  • 8 flights a week
  • Southwest Airlines

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When the nonstops leave

Typical weekly schedule · 8 flights per week · Updated 89d ago

Most leave in the afternoon.

Morning before noon 1 a week

Arrive the same day

11:00 AMSat
Afternoon noon – 6 PM 7 a week

Arrive the same day

4:45 PM
Evening after 6 PM 0 a week

No nonstop leaves after 6 PM.

Southwest Airlines Arrives Terminal 2

More nonstops from Charleston

CHS → ATL Atlanta CHS → BNA Nashville CHS → CMH Columbus CHS → HPN White Plains CHS → RIC Richmond CHS → ROC Rochester CHS → MCI Kansas City CHS → PBI West Palm Beach STL → CHS The return trip CHS All nonstops from Charleston STL All nonstops from St Louis

Frequently asked questions

Is there a direct flight from Charleston to St Louis?

Yes. Southwest Airlines flies nonstop from Charleston (CHS) to St Louis (STL), daily. The flight takes about 1h 57m and covers 705 miles (1,135 km). Schedule data from 21 July 2026.

Which airlines fly direct from Charleston to St Louis?

Southwest Airlines operates nonstop flights from Charleston to St Louis.

How long is the flight from Charleston to St Louis?

The nonstop flight from Charleston to St Louis takes ~1h 57m (approximately 1135 km).

How often do direct flights operate from Charleston to St Louis?

Nonstop flights from Charleston to St Louis operate daily — 8 flights per week.

What days of the week are there direct flights from Charleston to St Louis?

Direct flights from Charleston to St Louis operate every day of the week.