Is there a direct flight from Philadelphia to Knoxville/Maryville?

Yes, Allegiant Air and American Airlines operate nonstop flights from Philadelphia (PHL) to Knoxville/Maryville (TYS).

Which airlines fly direct from Philadelphia to Knoxville/Maryville?

Allegiant Air, American Airlines operate nonstop flights from Philadelphia to Knoxville/Maryville.

The nonstop flight from Philadelphia to Knoxville/Maryville takes ~1h 7m (approximately 891 km).

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✈ ~1h 7m 891 km PHL on-time 73.3% TYS on-time 67.6%

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Allegiant Air G4

American Airlines AA