Direct flights from Mexico City to Santiago MEX → SCL
LATAM flies nonstop from Mexico City (MEX) to Santiago (SCL), daily. The flight takes about 8h 57m and covers 4,099 miles (6,596 km). Round-trip fares typically run around $907. Fares last checked 20 August 2026.
60-day flexibility overview based on 2 recent fares across the next 60 days
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LATAM
LA
Nonstop departures observed in recent fares
Across 2 recent dates we priced, Mexico City (MEX) to Santiago (SCL) showed up to 1 nonstop departure a day, with the earliest around 09:55 and the latest around 20:05, operated by LATAM and Aeromexico.
09:55
20:05
Departure times seen while pricing this route over the last few weeks — a sample, not the full timetable. Airlines adjust schedules seasonally.
Frequently asked questions
Is there a direct flight from Mexico City to Santiago?
Yes, LATAM operates nonstop flights from Mexico City (MEX) to Santiago (SCL).
Which airlines fly direct from Mexico City to Santiago?
LATAM operates nonstop flights from Mexico City to Santiago.
How long is the flight from Mexico City to Santiago?
The nonstop flight from Mexico City to Santiago takes ~8h 57m (approximately 6596 km).
How often do direct flights operate from Mexico City to Santiago?
Nonstop flights from Mexico City to Santiago operate daily.
How much is a round-trip flight from Mexico City to Santiago?
Round-trip flights from Mexico City (MEX) to Santiago (SCL) start at $853, with a typical fare around $907. Based on 2 recent fare combinations.
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