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Yes. Aeromexico and Volaris fly nonstop from Mexico City (MEX) to Los Mochis (LMM), several times daily. The flight takes about 2h 5m and covers 771 miles (1,240 km).
Aeromexico, Volaris operate nonstop flights from Mexico City to Los Mochis.
The nonstop flight from Mexico City to Los Mochis takes ~2h 5m (approximately 1240 km).
Nonstop flights from Mexico City to Los Mochis operate several times daily.