Direct flights from Madrid to Santa Cruz MAD → VVI

Air Europa and BoA operate nonstop flights from Madrid (MAD) to Santa Cruz (VVI). The nonstop flight takes around ~11h 9m, covering 5,541 miles (8,917 km) and operates daily. Updated 28 June 2026.

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Boliviana de Aviación OB Air Europa UX

Departure Schedule next 7 days

Scheduled departures over the next 7 days · Updated 11d ago

Boliviana de Aviación
Wed
14:40
Sun, Mon, Wed, Fri
14:45
Air Europa
Sun, Mon, Wed, Fri, Sat
23:35

More nonstops from Madrid

MAD → LPA Gran Canaria Island 9 airlines MAD → ACE Lanzarote Island 6 airlines MAD → FCO Rome 5 airlines MAD → LIS Lisbon 5 airlines MAD → TNG Tangier 5 airlines MAD → BOG Bogotá 4 airlines MAD → CPH Copenhagen 4 airlines MAD → GRU São Paulo 4 airlines

Frequently asked questions

Is there a direct flight from Madrid to Santa Cruz?

Yes, Air Europa and BoA operate nonstop flights from Madrid (MAD) to Santa Cruz (VVI).

Which airlines fly direct from Madrid to Santa Cruz?

Air Europa, BoA operate nonstop flights from Madrid to Santa Cruz.

How long is the flight from Madrid to Santa Cruz?

The nonstop flight from Madrid to Santa Cruz takes ~11h 9m (approximately 8917 km).

How often do direct flights operate from Madrid to Santa Cruz?

Nonstop flights from Madrid to Santa Cruz operate daily.

Explore More

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