Direct flights from Madrid to Panama City

  • 10 flights a week
  • 2 airlines

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When the nonstops leave

Typical weekly schedule · 10 flights per week · Updated 129d ago

Most leave in the afternoon.

Morning before noon 0 a week

No nonstop leaves before noon.

Afternoon noon – 6 PM 10 a week
3:05 PM
3:55 PMWed, Fri, Sun
Evening after 6 PM 0 a week

No nonstop leaves after 6 PM.

Iberia
Air Europa

More nonstops from Madrid

MAD → LPA Gran Canaria Island 9 airlines MAD → ACE Lanzarote Island 6 airlines MAD → FRA Frankfurt-am-Main 6 airlines MAD → LIM Lima 6 airlines MAD → ORY Paris 4 airlines MAD → ATH Athens 3 airlines MAD → BOS Boston 3 airlines MAD → BUD Budapest 3 airlines PTY → MAD The return trip MAD All nonstops from Madrid PTY All nonstops from Panama City

Frequently asked questions

Is there a direct flight from Madrid to Panama City?

Yes. Air Europa and Iberia fly nonstop from Madrid (MAD) to Panama City (PTY), daily. The flight takes about 10h 57m and covers 5,069 miles (8,157 km). Schedule data from 12 June 2026.

Which airlines fly direct from Madrid to Panama City?

Air Europa, Iberia operate nonstop flights from Madrid to Panama City.

How long is the flight from Madrid to Panama City?

The nonstop flight from Madrid to Panama City takes ~10h 57m (approximately 8157 km).

How often do direct flights operate from Madrid to Panama City?

Nonstop flights from Madrid to Panama City operate daily — 10 flights per week.

What days of the week are there direct flights from Madrid to Panama City?

Direct flights from Madrid to Panama City operate every day of the week. Iberia flies Wednesday, Friday, and Sunday and Air Europa flies daily.