Is there a direct flight from London to Brindisi?

Yes, British Airways operates nonstop flights from London (LHR) to Brindisi (BDS).

Which airlines fly direct from London to Brindisi?

British Airways operates nonstop flights from London to Brindisi.

The nonstop flight from London to Brindisi takes ~2h 19m (approximately 1852 km).

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✈ ~2h 19m 1,852 km LHR on-time 97.8% BDS on-time 100.0%

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British Airways BA