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Yes. Turkish Airlines flies nonstop from Istanbul (IST) to Kastamonu (KFS), 3–4 times a week. The flight takes about 1h 3m and covers 263 miles (423 km).
Turkish Airlines operates nonstop flights from Istanbul to Kastamonu.
The nonstop flight from Istanbul to Kastamonu takes ~1h 3m (approximately 423 km).
Nonstop flights from Istanbul to Kastamonu operate 3–4 times a week.