Direct flights from Des Moines to Phoenix DSM → PHX
American Airlines and Southwest Airlines operate nonstop flights from Des Moines (DSM) to Phoenix (PHX). The nonstop flight takes around ~2h 19m, covering 1,148 miles (1,847 km). Round-trip fares currently start at $377, with a typical fare around $398 across 19 recent fare combinations. Updated 28 June 2026.
60-day flexibility overview based on 19 recent fares across the next 60 days
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American Airlines
AA
Southwest Airlines
WN
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Frequently asked questions
Is there a direct flight from Des Moines to Phoenix?
Yes, American Airlines and Southwest Airlines operate nonstop flights from Des Moines (DSM) to Phoenix (PHX).
Which airlines fly direct from Des Moines to Phoenix?
American Airlines, Southwest Airlines operate nonstop flights from Des Moines to Phoenix.
How long is the flight from Des Moines to Phoenix?
The nonstop flight from Des Moines to Phoenix takes ~2h 19m (approximately 1847 km).
How much is a round-trip flight from Des Moines to Phoenix?
Round-trip flights from Des Moines (DSM) to Phoenix (PHX) start at $377, with a typical fare around $398. Based on 19 recent fare combinations.