Direct flights from Denver to Knoxville/Maryville DEN → TYS

Frontier Airlines, United Airlines, Allegiant Air and Southwest Airlines operate nonstop flights from Denver (DEN) to Knoxville/Maryville (TYS). The nonstop flight takes around ~2h 20m, covering 1,159 miles (1,866 km) and operates daily. Updated 28 June 2026.

📬 Cheap nonstop deals from Denver

We'll email you when a fare from DEN drops well below normal. Free, weekly, no password needed.

Free · weekly digest · no password needed

Allegiant Air G4 Frontier Airlines F9 Southwest Airlines WN United Airlines UA

Departure Schedule next 7 days

More nonstops from Denver

DEN → SLC Salt Lake City 7 airlines DEN → ORD Chicago 6 airlines DEN → SEA Seattle 6 airlines DEN → CVG Cincinnati 5 airlines DEN → LAX Los Angeles 5 airlines DEN → MSP Minneapolis 5 airlines DEN → ATL Atlanta 4 airlines DEN → AUS Austin 4 airlines

Frequently asked questions

Is there a direct flight from Denver to Knoxville/Maryville?

Yes, Frontier Airlines, United Airlines and 2 more airlines operate nonstop flights from Denver (DEN) to Knoxville/Maryville (TYS).

Which airlines fly direct from Denver to Knoxville/Maryville?

Frontier Airlines, United Airlines, Allegiant Air, Southwest Airlines operate nonstop flights from Denver to Knoxville/Maryville.

How long is the flight from Denver to Knoxville/Maryville?

The nonstop flight from Denver to Knoxville/Maryville takes ~2h 20m (approximately 1866 km).

How often do direct flights operate from Denver to Knoxville/Maryville?

Nonstop flights from Denver to Knoxville/Maryville operate daily.

Explore More

DEN All direct flights from Denver 🗓 Find cheapest round-trip dates → TYS All direct flights from Knoxville/Maryville TYS → DEN Return: Knoxville/Maryville to Denver
Cheap direct deals from Denver — last one was $128 to Seattle